Bone marrow transplantation.

<p>Lethally irradiated 6-month-old mice were injected with bone marrow from 2-month-old donor mice through a tail vein. The engrafted mice were analyzed at 6 months after bone marrow transplantation. (A) Expression of inflammatory cytokines in the liver of WT→TAM^−/− mice. (B) Activities of serum ALT and AST in WT→TAM^−/− mice. (C) Cytokine expression in the liver of TAM^−/−→WT mice. (D) Serum AST and ALT activities in the TAM^−/−→WT mice. Total RNA was extracted from the liver, and the mRNAs of cytokines were determined by real-time RT-PCR. Serum AST and ALT activities were measured by enzymatic assay kits. (E) The expression of Axl in the circulating leukocytes in engrafted mice. Data are mean ± SEM (n = 10). **<i>P</i><0.01.