<p>Upper left: visual predictive check for peginesatide PK model following intravenous administration; Upper right: visual predictive check for peginesatide PK model following subcutaneous administration; Lower panel: visual predictive check for hemoglobin based on final population PK-PD model for peginesatide.</p
Peginesatide is an erythropoiesis stimulating agent (ESA) being developed for the treatment of anemi...
Peginesatide (OMONTYS®) is an erythropoiesis-stimulating agent that was indicated in the United Stat...
<p>(<b>a</b>) Visual predicive check (VPC) of the pharmacokinetic behavior using the posterior distr...
<p>Visual predictive check for the PK-PD model of peginesatide using traditional visual predictive c...
<p>Upper left (2A): measured concentration versus predicted concentration; Upper middle (2B): measur...
<p>(A) Prediction-corrected visual predictive check of the lumefantrine population pharmacokinetic m...
<p>Upper panel: effect of PK covariates on simulated peginesatide plasma concentrations; Middle and ...
The visual predictive checks were simulated for 1,000 patients and are shown for all 7 drugs and 9 l...
<p>The black circles represent the measured homocysteine concentrations relative to baseline. The so...
<p>The solid line represents the observed proportion with a more than 50% reduction in seizure frequ...
The red solid lines and circles correspond to the median observed concentration, while the dashed li...
Dots represent the observed linezolid concentrations; the solid lines correspond to the 5th, 50th, a...
<p>Visual predictive checks showing the medians (black lines) and corresponding 90% prediction inter...
Visual predictive check plots for (A) immediate-release (IR) tablet and (B) gastroretentive (GR) sys...
Peginesatide is an erythropoiesis stimulating agent (ESA) being developed for the treatment of anemi...
Peginesatide is an erythropoiesis stimulating agent (ESA) being developed for the treatment of anemi...
Peginesatide (OMONTYS®) is an erythropoiesis-stimulating agent that was indicated in the United Stat...
<p>(<b>a</b>) Visual predicive check (VPC) of the pharmacokinetic behavior using the posterior distr...
<p>Visual predictive check for the PK-PD model of peginesatide using traditional visual predictive c...
<p>Upper left (2A): measured concentration versus predicted concentration; Upper middle (2B): measur...
<p>(A) Prediction-corrected visual predictive check of the lumefantrine population pharmacokinetic m...
<p>Upper panel: effect of PK covariates on simulated peginesatide plasma concentrations; Middle and ...
The visual predictive checks were simulated for 1,000 patients and are shown for all 7 drugs and 9 l...
<p>The black circles represent the measured homocysteine concentrations relative to baseline. The so...
<p>The solid line represents the observed proportion with a more than 50% reduction in seizure frequ...
The red solid lines and circles correspond to the median observed concentration, while the dashed li...
Dots represent the observed linezolid concentrations; the solid lines correspond to the 5th, 50th, a...
<p>Visual predictive checks showing the medians (black lines) and corresponding 90% prediction inter...
Visual predictive check plots for (A) immediate-release (IR) tablet and (B) gastroretentive (GR) sys...
Peginesatide is an erythropoiesis stimulating agent (ESA) being developed for the treatment of anemi...
Peginesatide is an erythropoiesis stimulating agent (ESA) being developed for the treatment of anemi...
Peginesatide (OMONTYS®) is an erythropoiesis-stimulating agent that was indicated in the United Stat...
<p>(<b>a</b>) Visual predicive check (VPC) of the pharmacokinetic behavior using the posterior distr...