<p>. Particle size of complexes after incubation in (a, b) OptiMEM® or (c, d) 90% FBS. (a) and (b) depict 4 and 24 hours respectively. (c) and (d) depict co-formulated CD.siRNA complexes at molar ratios 1∶0 and 10∶1 respectively.</p
<p>Thermal denaturation curves of ternary complexes formed by the interaction of Cdk2/cyclin A and p...
<p>Cy3-labeled siRNA was complexed with galactosylated liposomes or naked siRNA and was subsequently...
<p>Error bars represent standard deviation of triplicates. (MR = C6M1:siRNA molar ratio)</p
<p>(a, b) Chemical structures and schematic representations of Cationic CD (a) and PEGylated CD (n =...
<p>Different amounts of heparin corresponding to final concentrations of 0.5 to 10 µg heparin per 10...
Polycations and cationic lipids have been widely employed as non-viral vectors for siRNA delivery. H...
<p>A) Stability of the C6M1-siRNA complexes to serum RNase degradation over time. Naked siRNA (top) ...
<p><b>A</b>) siRNA (100 pmol) or siRNA/dDAVP-9r polyplex at the various mole ratios were incubated i...
<p>(a) Cationic CD alone with no siRNA (magnification: x 60,000) (b) Cationic CD: PEGylated CD Molar...
<p>Apparent stability constants (Kc, M<sup>−1</sup>) and solubilization efficiency (Se) for the PAH-...
<p>Viability of mHypoE N41 neuronal cells after treatment with CD.siRNA complexes (MR 20 cationic CD...
<p>A and C, Chemically synthesized RNA or DNA fragments of similar sequence and length (7 pmol) were...
<p>(<b>A</b>) varying complex dose (0.5 and 1.0 µg/mL siRNA). (<b>B</b>) varying polymer:siRNA weigh...
<p>Percentage of plasmid DNA association as a function of cationic lipopolymer/pCH110 (a and b) or p...
<p>A) SIR complexes as indicated were purified form co-infected insect cells. 1 µg of each complex w...
<p>Thermal denaturation curves of ternary complexes formed by the interaction of Cdk2/cyclin A and p...
<p>Cy3-labeled siRNA was complexed with galactosylated liposomes or naked siRNA and was subsequently...
<p>Error bars represent standard deviation of triplicates. (MR = C6M1:siRNA molar ratio)</p
<p>(a, b) Chemical structures and schematic representations of Cationic CD (a) and PEGylated CD (n =...
<p>Different amounts of heparin corresponding to final concentrations of 0.5 to 10 µg heparin per 10...
Polycations and cationic lipids have been widely employed as non-viral vectors for siRNA delivery. H...
<p>A) Stability of the C6M1-siRNA complexes to serum RNase degradation over time. Naked siRNA (top) ...
<p><b>A</b>) siRNA (100 pmol) or siRNA/dDAVP-9r polyplex at the various mole ratios were incubated i...
<p>(a) Cationic CD alone with no siRNA (magnification: x 60,000) (b) Cationic CD: PEGylated CD Molar...
<p>Apparent stability constants (Kc, M<sup>−1</sup>) and solubilization efficiency (Se) for the PAH-...
<p>Viability of mHypoE N41 neuronal cells after treatment with CD.siRNA complexes (MR 20 cationic CD...
<p>A and C, Chemically synthesized RNA or DNA fragments of similar sequence and length (7 pmol) were...
<p>(<b>A</b>) varying complex dose (0.5 and 1.0 µg/mL siRNA). (<b>B</b>) varying polymer:siRNA weigh...
<p>Percentage of plasmid DNA association as a function of cationic lipopolymer/pCH110 (a and b) or p...
<p>A) SIR complexes as indicated were purified form co-infected insect cells. 1 µg of each complex w...
<p>Thermal denaturation curves of ternary complexes formed by the interaction of Cdk2/cyclin A and p...
<p>Cy3-labeled siRNA was complexed with galactosylated liposomes or naked siRNA and was subsequently...
<p>Error bars represent standard deviation of triplicates. (MR = C6M1:siRNA molar ratio)</p