CLDN3 and CLDN4 regulate the expression of EMT markers.

<p>(A) Western blot analysis of the expression of E-cadherin and mesenchymal markers N-cadherin and vimentin in the scrambled control 2008 (2008-scb), CLDN3KD and CLDN4KD cells. (B) Western blot analysis of the levels of EMT-inducing transcription factors. The histograms indicate the levels of the protein determined from 3 independent experiments expressed as the mean ratio relative to that in the 2008-scb cells after normalization to α-tubulin. Values are mean ± SEM. *p<0.05 <i>versus</i> 2008-scb; **p<0.01 <i>versus</i> 2008-scb.