<p>Vps33, Vps16<sub>CTD</sub>–Vps33, rat Munc18–1 (PDB entry 3PUJ), and Sly1 (1MQS) are shown with cylinders representing α-helices. The different position of domain 1 in Vps33, relative to Munc18–1 and Sly1, is especially notable. The tip of domain 3a shows varying degrees of disorder, as discussed in the text.</p
Intracellular membrane fusion requires the regulated assembly of SNARE (soluble N-ethylmaleimide-sen...
Small heat shock proteins (sHsps) are a family of large and dynamic oligomers highly expressed in lo...
VPS33B protein is a homologue of the yeast class C vacuolar protein sorting protein Vps33p that is i...
<p>(A) All known SM protein structures (PDB entries 1EPU, 1FVF, 1MQS, 2XHE, 3C98, 3PUJ, and 3PUK), i...
<p>(A) Highly conserved residues were determined by comparing the sequences of fifteen Vps33 ortholo...
<p>(<b>A</b>) and (<b>B</b>) overall view of the superimposition of the MASP-3 SP domain with differ...
<p>(<b>A</b>) Modeled molecular structures of the extracellular domains with striking similarity wit...
<p>The structural characteristics of two orthologous protein pairs from the COPII vesicle traffickin...
<p>Root mean square deviation (RMSD) and number of superimposable alpha carbons (Cα) are reported be...
<p>Three PDB structures are presented showing the interaction between distinct pairs of the syntaxin...
<p>A: Red balls represent protein sector 1, which mainly comprises residues located near the catalyt...
<p><b>(A)</b> Names and positions of the six domains on the primary sequence: NTD (N-terminal domain...
Spinal muscular atrophy (SMA) is a motor neuron disease that leads to muscle atrophy due to motor ne...
<p>Ribbon representation of the domains with superimposed backbone, MLL5<sub>PHD</sub> in blue and u...
<p>Selected misfolded dimeric tandems obtained from the simulations (right column) are compared with...
Intracellular membrane fusion requires the regulated assembly of SNARE (soluble N-ethylmaleimide-sen...
Small heat shock proteins (sHsps) are a family of large and dynamic oligomers highly expressed in lo...
VPS33B protein is a homologue of the yeast class C vacuolar protein sorting protein Vps33p that is i...
<p>(A) All known SM protein structures (PDB entries 1EPU, 1FVF, 1MQS, 2XHE, 3C98, 3PUJ, and 3PUK), i...
<p>(A) Highly conserved residues were determined by comparing the sequences of fifteen Vps33 ortholo...
<p>(<b>A</b>) and (<b>B</b>) overall view of the superimposition of the MASP-3 SP domain with differ...
<p>(<b>A</b>) Modeled molecular structures of the extracellular domains with striking similarity wit...
<p>The structural characteristics of two orthologous protein pairs from the COPII vesicle traffickin...
<p>Root mean square deviation (RMSD) and number of superimposable alpha carbons (Cα) are reported be...
<p>Three PDB structures are presented showing the interaction between distinct pairs of the syntaxin...
<p>A: Red balls represent protein sector 1, which mainly comprises residues located near the catalyt...
<p><b>(A)</b> Names and positions of the six domains on the primary sequence: NTD (N-terminal domain...
Spinal muscular atrophy (SMA) is a motor neuron disease that leads to muscle atrophy due to motor ne...
<p>Ribbon representation of the domains with superimposed backbone, MLL5<sub>PHD</sub> in blue and u...
<p>Selected misfolded dimeric tandems obtained from the simulations (right column) are compared with...
Intracellular membrane fusion requires the regulated assembly of SNARE (soluble N-ethylmaleimide-sen...
Small heat shock proteins (sHsps) are a family of large and dynamic oligomers highly expressed in lo...
VPS33B protein is a homologue of the yeast class C vacuolar protein sorting protein Vps33p that is i...
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