Transcriptome analysis utilizing microarray of stimulated CD4, CD8 and DN T cells from uninfected mangabeys demonstrates relatedness of CD4 and DN T cells.

<p>A) Heat map and hierarchical cluster analysis of genes that were differentially regulated over 4 fold are depicted for DN (lane 1), CD4 (lane 2) and CD8 T cells (lane 3). Red indicates upregulation and green indicates down regulation for each gene listed on the right. B) Venn Diagram representing overlap of differentially regulated genes (2 fold) identified from the microarray analysis of CD4, CD8 and DN T cells stimulated through their TCR (anti CD3/CD28).