<p>A) Representative contour plots showing surface expression of CD4 and CD8 molecules on <i>ex vivo</i> circulating T and Vα24<sup>+</sup>CD1d TM<sup>+</sup> NKT lymphocytes in two sooty mangabeys (SM #1 and SM #2). B) Contour plots showing surface expression pattern of CD4 and CD8 molecules on representative NKT clones. C) Distribution of CD4<sup>+</sup> (CD4<sup>+</sup>8<sup>−</sup>), CD8<sup>+</sup> (CD8<sup>+</sup>4<sup>−</sup>), DN (CD4<sup>−</sup>8<sup>−</sup>) and DP (CD4<sup>+</sup>8<sup>+</sup>) T lymphocyte subsets in <i>ex vivo</i> NKT lymphocytes in 13 SIV-negative sooty mangabeys (left panel) and in 57 NKT clones derived from sorted 6B11<sup>+</sup> T lymphocytes of one SIV-negative sooty mangabey (right panel).</p
<p>Contour plots showing CD4 and CD8 expression on NKT lymphocytes from 3 SIV-negative CM (CM1, CM2 ...
<p>A) Representative flow cytometry plot of IFNγ protein expression (x-axis) and IL4 protein express...
<p>A) Cytokine ELISA for IFN-γ, IL-2, IL-10, IL-13, and IL-4 with culture supernatants collected 24 ...
<p>A) Representative dot plots showing gating strategy for identification of NKT lymphocytes. On the...
<p>A) Histogram plots gated on representative NKT clones showing surface expression of NK cell marke...
<p>*Paired <i>t</i>-test.</p><p><sup>@</sup>Mean % and Standard Deviation in 13 SIV-negative sooty m...
<p>A) Dot-plots of <i>ex vivo</i> peripheral blood NKT lymphocytes in one SIV-negative sooty mangabe...
<p>Cytokine ELISA for IFN-γ, IL-2, IL-13, IL-10, IL-6, and TGF-β with culture supernatants collected...
<p>A) Percentage of total NKT lymphocytes in peripheral blood T lymphocytes of SIV-negative and SIV-...
<p>A) Intracellular cytokine staining of one representative NKT clone with antibodies against IFN-γ,...
Lack of chronic immune activation in the presence of persistent viremia is a key feature that distin...
<p>A) IFN-γ ELISA on culture supernatants of NKT clones stimulated with C1R.d/α-GalCer (50 ng/ml) fo...
Lack of chronic immune activation in the presence of persistent viremia is a key feature that distin...
<p>A) Heat map and hierarchical cluster analysis of genes that were differentially regulated over 4 ...
Summary: Our understanding of human type 1 natural killer T (NKT) cells has been heavily dependent o...
<p>Contour plots showing CD4 and CD8 expression on NKT lymphocytes from 3 SIV-negative CM (CM1, CM2 ...
<p>A) Representative flow cytometry plot of IFNγ protein expression (x-axis) and IL4 protein express...
<p>A) Cytokine ELISA for IFN-γ, IL-2, IL-10, IL-13, and IL-4 with culture supernatants collected 24 ...
<p>A) Representative dot plots showing gating strategy for identification of NKT lymphocytes. On the...
<p>A) Histogram plots gated on representative NKT clones showing surface expression of NK cell marke...
<p>*Paired <i>t</i>-test.</p><p><sup>@</sup>Mean % and Standard Deviation in 13 SIV-negative sooty m...
<p>A) Dot-plots of <i>ex vivo</i> peripheral blood NKT lymphocytes in one SIV-negative sooty mangabe...
<p>Cytokine ELISA for IFN-γ, IL-2, IL-13, IL-10, IL-6, and TGF-β with culture supernatants collected...
<p>A) Percentage of total NKT lymphocytes in peripheral blood T lymphocytes of SIV-negative and SIV-...
<p>A) Intracellular cytokine staining of one representative NKT clone with antibodies against IFN-γ,...
Lack of chronic immune activation in the presence of persistent viremia is a key feature that distin...
<p>A) IFN-γ ELISA on culture supernatants of NKT clones stimulated with C1R.d/α-GalCer (50 ng/ml) fo...
Lack of chronic immune activation in the presence of persistent viremia is a key feature that distin...
<p>A) Heat map and hierarchical cluster analysis of genes that were differentially regulated over 4 ...
Summary: Our understanding of human type 1 natural killer T (NKT) cells has been heavily dependent o...
<p>Contour plots showing CD4 and CD8 expression on NKT lymphocytes from 3 SIV-negative CM (CM1, CM2 ...
<p>A) Representative flow cytometry plot of IFNγ protein expression (x-axis) and IL4 protein express...
<p>A) Cytokine ELISA for IFN-γ, IL-2, IL-10, IL-13, and IL-4 with culture supernatants collected 24 ...