Glucose tolerance test.

<p>A group of young diabetic rats was treated with 0.8 µg/gm TA1m by high pressure tail vein injection, as described in methods. Control groups included age-matched STZ-diabetic and normal rats. Four days after TA1m treatment, all rats were fasted and intraperitoneally injected with 4gm glucose/kg body weight. Blood samples over a 2 hr period at the indicated time intervals were collected from each experimental rat, blood glucose and plasma levels of human insulin were measured. Fig. 10A: open black circle, blood glucose levels (mg/dl); open blue diamond, plasma insulin levels (mU/L). Blood glucose levels in normal control rats (black filled square) and STZ-diabetic rats (red filled circle) subjected to intraperitoneal glucose tolerance test are shown in Fig. 10B.