<p> The first five panels show results from the stochastic model with varying values of 20, 40, 60, 80, 100 (left to right); the final panel shows results from the deterministic model. values (<i>x</i>-axis) range from 0 to 4000, / ratio (<i>y</i>-axis) ranges from 0 to 10. Blue indicates accurate tracking (>70% probability), red indicates narrow width ( FWHM), purple indicates that both criteria are met and white indicates that neither criterion is met. As the number of actin cables is increased, the stochastic phenotype plots converge to the deterministic plot. Lower actin cable number confers a larger region where both criteria are satisfied, indicating that increased stochasticity leads to more robustness to parameter variation. For e...
<p>The cell is initiated at rest, stimulated for 10 sec with a 15% gradient in the Cdc42 basal activ...
<p>A: <i>cla4</i>Δ cells were exposed to <i>α</i>-factor for varying amounts of time to observe a se...
<p><b>A.</b> A schematic diagram of the reaction-diffusion model with the following parameters: <i>D...
<p>(<b>A</b>) Yeast cells treated with -factor show the wider Cdc42a (marked by Ste20-GFP) and tight...
<p>(A) Using the data from <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcb...
<p>(A) LEGI-Biased excitable network with polarity. (B) Signaling activity (<i>Y</i>) around the cel...
<p>Bifurcation plots showing polarization, measured by <i>H</i>(<i>r</i> = 0.5 μm), versus parameter...
<p><b>A and B)</b> Increasing the strength of pheromone stimulation (S) leads to increasing levels o...
Although cell polarity is an essential feature of living cells, it is far from being well-understood...
Although cell polarity is an essential feature of living cells, it is far from being well-understood...
<p><b>A,B</b> Polarization capability predicted from the linear stability analysis shown for differe...
<p><b>Columns:</b> WT phenotype (<b>left</b>), phenotype (<b>right</b>). (<b>A</b>) <i>In vivo</i> ...
Cell polarization is an important part of the response of eukaryotic cells to stimuli, and forms a p...
<p><b>(a)</b> Threshold relationship between the amplitude and duration of stimuli for inducing cell...
Patterns are ubiquitous in nature, but the underlying mechanisms giving rise to them are not always ...
<p>The cell is initiated at rest, stimulated for 10 sec with a 15% gradient in the Cdc42 basal activ...
<p>A: <i>cla4</i>Δ cells were exposed to <i>α</i>-factor for varying amounts of time to observe a se...
<p><b>A.</b> A schematic diagram of the reaction-diffusion model with the following parameters: <i>D...
<p>(<b>A</b>) Yeast cells treated with -factor show the wider Cdc42a (marked by Ste20-GFP) and tight...
<p>(A) Using the data from <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcb...
<p>(A) LEGI-Biased excitable network with polarity. (B) Signaling activity (<i>Y</i>) around the cel...
<p>Bifurcation plots showing polarization, measured by <i>H</i>(<i>r</i> = 0.5 μm), versus parameter...
<p><b>A and B)</b> Increasing the strength of pheromone stimulation (S) leads to increasing levels o...
Although cell polarity is an essential feature of living cells, it is far from being well-understood...
Although cell polarity is an essential feature of living cells, it is far from being well-understood...
<p><b>A,B</b> Polarization capability predicted from the linear stability analysis shown for differe...
<p><b>Columns:</b> WT phenotype (<b>left</b>), phenotype (<b>right</b>). (<b>A</b>) <i>In vivo</i> ...
Cell polarization is an important part of the response of eukaryotic cells to stimuli, and forms a p...
<p><b>(a)</b> Threshold relationship between the amplitude and duration of stimuli for inducing cell...
Patterns are ubiquitous in nature, but the underlying mechanisms giving rise to them are not always ...
<p>The cell is initiated at rest, stimulated for 10 sec with a 15% gradient in the Cdc42 basal activ...
<p>A: <i>cla4</i>Δ cells were exposed to <i>α</i>-factor for varying amounts of time to observe a se...
<p><b>A.</b> A schematic diagram of the reaction-diffusion model with the following parameters: <i>D...