Decrease of IL-1α, IL-4, IL-6, IL-8 and IL-10 concentration in plasma is observed in the CPA group (n = 7) compare to the control group (n = 25).

<p>Log₂ of the cytokine concentration normalized on the total amount of protein in plasma for each subject in each aggressive group is shown for 10 cytokines. Each boxplot represents the median (line), lower and upper quartiles (grey boxes), 95% confidence intervals (T-bars) and possible outliers (°) for each aggressive group per cytokine. Significant group difference was determined using student T-test with Bonferroni correction (α ≤0.005) and bootstrap (see methods). CPA indicates the chronic physical aggression trajectory group and CG the control group. MANOVA combining all 10 cytokines: <i>F</i>(10) = 2.9, <i>P</i> = 0.019. *** <i>P</i>≤0.0001, ** <i>P</i>≤0.001, * <i>P</i>≤0.005, # <i>P</i>≤0.01 from Student T-test (two-tailed).