Comparative survival curves of mice injected with TcdB₀₀₃ and TcdB_027.

<p>Kaplan-Meier graphs showing the time to death of BALB/c mice that were injected intravenously with TcdB. (A) Survival time of mice (n = 4) injected with 50 ug/kg, 25 ug/kg, 5 ug/kg, and 2.5 ug/kg of TcdB₀₀₃. (B) Survival time of mice (n = 4) injected with 10 ug/kg, 5 ug/kg, 2.5 ug/kg, 1.25 ug/kg, and 625 ng/kg of TcdB₀₂₇. (C) Kaplan-Meier graph comparing the time to death of mice injected with 5 ug/kg of TcdB₀₀₃ or TcdB₀₂₇. The difference between the curves is indicated by the p value determined from a log-rank analysis. (D) Kaplan-Meier graph comparing the time to death of mice injected with 2.5 ug/kg of TcdB₀₀₃ or TcdB₀₂₇. The difference between the curves is indicated by the p value determined from a log-rank analysis.