v63G/70R replicates comparable to parental virus in vitro.

<p>(A) Replication kinetics of parental P-Oka (rOKA) and v63G/70R in MeWo cells. Data is shown as mean viral titers with standard deviations (error bars). (B) Replication of v63G/70R in NHNP TLAs. NHNP TLAs were infected with v63G/70R in triplicate, samples removed at the indicated time points and analyzed by qPCR. Data is shown as mean viral genome copies with standard deviations (error bars). (C) Daily glucose utilization of MeWo cells and NHNP TLAs prior and post infection with v63G/70R at day 39. Passages of MeWo cells are indicated with an arrow. Data is shown as mean glucose utilization levels with standard deviations (error bars).