<p>(A,E) Control and (B,F) 670nm alone mice retina showed no observable difference in peripheral retinal vasculature, while (C,G) OIR alone showed increaed vaso-obliteration (indicated by <b>+</b>) and neovascularisation (indicated by arrowheads). There was also an observable vascular organisational difffernce in the OIR exposed retina (G). (D, H) 670nm+OIR, showed amelioration of neovascularisation, vaso-obliteration and a more uniform vascular patterning. P – postnatal day, OIR - Oxygen induced retinopathy. Scale A - D = 1mm, E -H = 200µm, I. Magnification of images E-H are 4x original images.</p
Abnormal blood vessel growth in the retina is a hallmark of many retinal diseases, such as retinopat...
<p><b>A</b>) Retinas were harvested from OIR mice at P12 (<b>left</b>), P15 (<b>center</b>) and P17 ...
<p>Retinal cross sections were prepared at 4 w and 8 w. (A) Hematoxylin and eosin staining. Scale ba...
<p>(A,E) Control and (B,F) 670nm alone mice retina showed no observable difference in peripheral ret...
<p>Mice were perfused with fluorescein-labeled dextran. Normal mice were analyzed P2 [A], P4 [B], an...
<p>Mice were raised in room air and at P12, P17, and P25 whole mounted retinas were stained with Ale...
<p>C57BL/6 and IL-10<sup>−/−</sup> were exposed to 75%±2% O<sub>2</sub> from day P7 to P12. Mice wer...
<p>Wild type and <i>Fzd4</i><sup>+/-</sup> mice were exposed to our OIR model from P7 to P12 and ret...
<p>Control (CTL) mice housed under normal room air oxygen saturation showed fully grown retinal vess...
<p>Wild type and <i>Fzd4</i><sup>+/-</sup> mice were exposed to our OIR model from P7 to P12 and ret...
<p>C57Bl/6 mouse pups were exposed to 75% oxygen from P7 to P12 to induce retinopathy. Littermate mo...
Clifford B Kim,1,2 Patricia A D’Amore,2–4 Kip M Connor1,2 1Angiogenesis Laboratory, Mass...
<div><p>Retinal ischemia and pathological angiogenesis cause severe impairment of sight. Oxygen-indu...
PURPOSE: To develop oxygen-induced retinopathy in the mouse with reproducible and quantifiable proli...
<p><i>Tie2-Sirt1<sup>OE</sup></i> and littermate control mice were exposed to 75% oxygen from P7 to ...
Abnormal blood vessel growth in the retina is a hallmark of many retinal diseases, such as retinopat...
<p><b>A</b>) Retinas were harvested from OIR mice at P12 (<b>left</b>), P15 (<b>center</b>) and P17 ...
<p>Retinal cross sections were prepared at 4 w and 8 w. (A) Hematoxylin and eosin staining. Scale ba...
<p>(A,E) Control and (B,F) 670nm alone mice retina showed no observable difference in peripheral ret...
<p>Mice were perfused with fluorescein-labeled dextran. Normal mice were analyzed P2 [A], P4 [B], an...
<p>Mice were raised in room air and at P12, P17, and P25 whole mounted retinas were stained with Ale...
<p>C57BL/6 and IL-10<sup>−/−</sup> were exposed to 75%±2% O<sub>2</sub> from day P7 to P12. Mice wer...
<p>Wild type and <i>Fzd4</i><sup>+/-</sup> mice were exposed to our OIR model from P7 to P12 and ret...
<p>Control (CTL) mice housed under normal room air oxygen saturation showed fully grown retinal vess...
<p>Wild type and <i>Fzd4</i><sup>+/-</sup> mice were exposed to our OIR model from P7 to P12 and ret...
<p>C57Bl/6 mouse pups were exposed to 75% oxygen from P7 to P12 to induce retinopathy. Littermate mo...
Clifford B Kim,1,2 Patricia A D’Amore,2–4 Kip M Connor1,2 1Angiogenesis Laboratory, Mass...
<div><p>Retinal ischemia and pathological angiogenesis cause severe impairment of sight. Oxygen-indu...
PURPOSE: To develop oxygen-induced retinopathy in the mouse with reproducible and quantifiable proli...
<p><i>Tie2-Sirt1<sup>OE</sup></i> and littermate control mice were exposed to 75% oxygen from P7 to ...
Abnormal blood vessel growth in the retina is a hallmark of many retinal diseases, such as retinopat...
<p><b>A</b>) Retinas were harvested from OIR mice at P12 (<b>left</b>), P15 (<b>center</b>) and P17 ...
<p>Retinal cross sections were prepared at 4 w and 8 w. (A) Hematoxylin and eosin staining. Scale ba...