Histological examination of conceptuses from mice with intrauterine and extrauterine infections.

<p>Hematoxylin/eosin stained sections of the conceptuses from two of five mice identified in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0072601#tab2" target="_blank">Table 2</a> are shown. (A) Uterus and placenta (200x magnification) of mouse 2 with no detected uterine cfu: no lesions were noted. (B) Uterus and placenta (200x magnification) from mouse 7, showing > 10⁶ uterine listerial cfu. The arrow heads denote inflammation and necrosis indicated by the degenerative neutrophils mixed with cellular debris and fibrin that have focally effaced the chorionic plate. The arrow identifies an infected giant trophoblast that has intracellular gram positive rods (see Gram-stained inset: 1000x).