<p>A) Patch assay of dityrosine fluorescence. Single and multiple mutant diploid cells of the indicated genotypes were sporulated on filters and the filter was exposed to UV light to detect dityrosine fluorescence. B) Quantitation of dityrosine fluorescence in the paralog mutant strains. Dityrosine fluorescence from the spore wall was quantified for strains of the indicated genotypes using a fluorescence microscopy assay. For each strain, the fluorescence value represents the average of twenty individual cells. Error bars indicate one standard deviation. Multiple mutant diploids are indicated by the name of the set of genes deleted as listed in <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1003700#pgen-1003700-t...
<p>A. Quantitative recombination assays of deletion strains expressing wild-type Tf1-<i>nat</i>AI an...
<p>Light grey, 2N – diploid strain and its derivatives containing one or several supernumerary chrom...
<p>(A) Comparison of dNTP levels. Relative dNTP levels were determined in the indicated strains of c...
<p>Cytoscape was used to represent the genetic interactions listed in Table S1. Lines between the ci...
<p>Strains of the indicated genotypes were sporulated in liquid to >70% asci and then 10-fold serial...
<p>(A) The effect of each mutant genotype on YFP fluorescence in haploid cells (X-axis) is compared ...
<p>(A) Overlay of phase-contrast and fluorescence images showing a microcolony containing fluorescen...
<p>Strains of the indicated genotype were sporulated and stained with both Eosin Y and Calcofluor Wh...
<p>The effects on YFP fluorescence of the 4 <i>cis</i>-regulatory (black), 16 coding (green), 22 CNV...
<p>(A, B) A synthetic sick phenotype arises when deletion of <i>SCH9</i> is combined with a fully dy...
<p>(A) Fluorescence microscopy images corresponding to the Nile Red -stained strains <i>E</i>. <i>co...
Mutagenesis in model organisms following exposure to chemicals is used as an indicator of genotoxici...
<p>Strain W303C (A1, A2), and isogenic mutants W303-Δ<i>syr2</i> (<i>sur2</i>) (B1, B2), W303-Δe<i>l...
<p>(A) Representative immunofluorescent images showing the distribution of dityrosine in embryos of ...
<p>Cells of wild-type and mutant strains (<a href="http://www.plosone.org/article/info:doi/10.1371/j...
<p>A. Quantitative recombination assays of deletion strains expressing wild-type Tf1-<i>nat</i>AI an...
<p>Light grey, 2N – diploid strain and its derivatives containing one or several supernumerary chrom...
<p>(A) Comparison of dNTP levels. Relative dNTP levels were determined in the indicated strains of c...
<p>Cytoscape was used to represent the genetic interactions listed in Table S1. Lines between the ci...
<p>Strains of the indicated genotypes were sporulated in liquid to >70% asci and then 10-fold serial...
<p>(A) The effect of each mutant genotype on YFP fluorescence in haploid cells (X-axis) is compared ...
<p>(A) Overlay of phase-contrast and fluorescence images showing a microcolony containing fluorescen...
<p>Strains of the indicated genotype were sporulated and stained with both Eosin Y and Calcofluor Wh...
<p>The effects on YFP fluorescence of the 4 <i>cis</i>-regulatory (black), 16 coding (green), 22 CNV...
<p>(A, B) A synthetic sick phenotype arises when deletion of <i>SCH9</i> is combined with a fully dy...
<p>(A) Fluorescence microscopy images corresponding to the Nile Red -stained strains <i>E</i>. <i>co...
Mutagenesis in model organisms following exposure to chemicals is used as an indicator of genotoxici...
<p>Strain W303C (A1, A2), and isogenic mutants W303-Δ<i>syr2</i> (<i>sur2</i>) (B1, B2), W303-Δe<i>l...
<p>(A) Representative immunofluorescent images showing the distribution of dityrosine in embryos of ...
<p>Cells of wild-type and mutant strains (<a href="http://www.plosone.org/article/info:doi/10.1371/j...
<p>A. Quantitative recombination assays of deletion strains expressing wild-type Tf1-<i>nat</i>AI an...
<p>Light grey, 2N – diploid strain and its derivatives containing one or several supernumerary chrom...
<p>(A) Comparison of dNTP levels. Relative dNTP levels were determined in the indicated strains of c...