Power and accuracy for simulated data.

<p>The plot shows true positive rates (TPR; fraction of true gBGC bases correctly predicted) and positive predictive values (PPV; fraction of predicted bases in true gBGC tracts) as a function of tract length. Results are shown for two sets of simulations, one assuming strong BGC (), and the other assuming weaker BGC () (see <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1003684#s4" target="_blank">Methods</a>). Both the power (as measured by the TPR) and the accuracy (as measured by PPV) of gBGC detection depend strongly on tract length. At shorter lengths (less than 3000 bp) power also depends strongly on the strength of gBGC, while accuracy does not. Both TPR and PPV are fairly high (80% or more) for tracts longer than 1 kb that have experienced strong gBGC, and for tracts longer than 1.6 kb that have experienced weaker gBGC.