<p>a) Binding of <sup>125</sup>I labeled TNF to HT1080 cells. b) Scatchard blot of binding of <sup>125</sup>I labeled TNF to HT1080 cells. c) Inhibition of binding of <sup>125</sup>I labeled TNF to HT1080 cells by ATROSAB at 4°C and 37°C, respectively. Displayed are mean values and SD of three individual experiments in percent of maximal TNF binding.</p
<p>Comparative data table of top 35 inhibitors selected from MK2-EGFP translocation assay (TA) deter...
<p>HUVEC were incubated with indicated concentrations of NaHS, Dex (10 µM) or NAC (5 mM) for 30 min,...
<p>(A) Western-assisted analysis of ATF4, CHOP, P-NF-κB p65, IκBα, SCOS3, p-ERK1/2 and β-Actin. Repr...
<p>Details of binding studies are described in <a href="http://www.plosone.org/article/info:doi/10.1...
Selective inhibition of TNFR1 signaling holds the potential to greatly reduce the pro-inflammatory a...
<p>TNFα activity was assessed by measuring cell viability (n = 3) using the XTT assay on L929 sensit...
<p>EC were treated with 100 nM MaR1 for 30 min followed by 18 hr of TNF-α (1 ng/ml), after which the...
<p>A: B: The number of TUNEL positive cells/field after exposure to 50 ng/ml of TNF-α is not signifi...
<p>binding to the receptor mutants compared to huTNFR1-Fc is indicated as similar (+) or strongly re...
(A) Upper panels—images of podocytes treated with 10% serum from a patient with podocyte toxic activ...
<p>a) SEC of purified Htr-9. b) ELISA analyzing binding of Htr-9 and ATROSAB to immobilized human an...
A) Western blot assays performed on U87 cell lysates in the control condition and after treatment wi...
<p>A) SK-N-MC cells were stimulated during the indicated time with TNF-α (20 ng/ml). Cell lysates we...
<p>Panel A - Enhanced expression of TNFR1 following treatment with rHP986; Panel B - HP986 did not s...
<p>Binding of ATROSAB to human TNFR1 was analyzed by QCM at high (a, b; 130 Hz) and low (c, d; 27 Hz...
<p>Comparative data table of top 35 inhibitors selected from MK2-EGFP translocation assay (TA) deter...
<p>HUVEC were incubated with indicated concentrations of NaHS, Dex (10 µM) or NAC (5 mM) for 30 min,...
<p>(A) Western-assisted analysis of ATF4, CHOP, P-NF-κB p65, IκBα, SCOS3, p-ERK1/2 and β-Actin. Repr...
<p>Details of binding studies are described in <a href="http://www.plosone.org/article/info:doi/10.1...
Selective inhibition of TNFR1 signaling holds the potential to greatly reduce the pro-inflammatory a...
<p>TNFα activity was assessed by measuring cell viability (n = 3) using the XTT assay on L929 sensit...
<p>EC were treated with 100 nM MaR1 for 30 min followed by 18 hr of TNF-α (1 ng/ml), after which the...
<p>A: B: The number of TUNEL positive cells/field after exposure to 50 ng/ml of TNF-α is not signifi...
<p>binding to the receptor mutants compared to huTNFR1-Fc is indicated as similar (+) or strongly re...
(A) Upper panels—images of podocytes treated with 10% serum from a patient with podocyte toxic activ...
<p>a) SEC of purified Htr-9. b) ELISA analyzing binding of Htr-9 and ATROSAB to immobilized human an...
A) Western blot assays performed on U87 cell lysates in the control condition and after treatment wi...
<p>A) SK-N-MC cells were stimulated during the indicated time with TNF-α (20 ng/ml). Cell lysates we...
<p>Panel A - Enhanced expression of TNFR1 following treatment with rHP986; Panel B - HP986 did not s...
<p>Binding of ATROSAB to human TNFR1 was analyzed by QCM at high (a, b; 130 Hz) and low (c, d; 27 Hz...
<p>Comparative data table of top 35 inhibitors selected from MK2-EGFP translocation assay (TA) deter...
<p>HUVEC were incubated with indicated concentrations of NaHS, Dex (10 µM) or NAC (5 mM) for 30 min,...
<p>(A) Western-assisted analysis of ATF4, CHOP, P-NF-κB p65, IκBα, SCOS3, p-ERK1/2 and β-Actin. Repr...