<p><i>h</i><sup>2</sup>: variance explained by the locus.</p><p>a: in case-control samples, 50% of the sample are cases, P = 0.5.</p><p>Exp: Expected power based on NCP derived from <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0071494#pone.0071494.e002" target="_blank">equation (1</a>)∼(4).</p><p>Obs: Averaged power over 10000 replicates of simulation.</p><p>SE: Empirical standard error over 10000 replicates.</p
<p>Power of detection for the different 2-locus models. Power was estimated as the proportion of ite...
<p>These values were averaged over ten simulations each. Note that these values differ slightly from...
The empirical power for scenarios (i)—(v) under nominal significance level 0.05 based on 10,000 repl...
<p>Exp1: Expected value from <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0...
Abstract Background Phenome-wide association studies (PheWAS) are a high-throughput approach to eval...
<p>Exp1: Expected value from <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0...
<p>Power was estimated at the nominal level of 5% based on 1,000 replicates. The value of <i>r</i><s...
<p>For each simulation setting where (or, equivalently, ), power was assessed by tracking the perce...
<p>Exp1: Expected value from <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0...
<p>For each effect size (1,2,3,4,5 or 10% of the total variance) 100 simulations were carried out. T...
<p>For each effect size (1,2,3,4,5 or 10% of the total variance) 100 simulations were carried out. T...
<p>For each effect size (1,2,3,4,5 or 10% of the total variance) 100 simulations were carried out. T...
<p>Results were based on 200 replicates. In each replicate, 500 cases and 500 controls were used to ...
<p>The figure shows the empirical power given the significance level of 0.05. Top row: 50 variants i...
The power of a statistical test is the probability that it will yield a statistically significant re...
<p>Power of detection for the different 2-locus models. Power was estimated as the proportion of ite...
<p>These values were averaged over ten simulations each. Note that these values differ slightly from...
The empirical power for scenarios (i)—(v) under nominal significance level 0.05 based on 10,000 repl...
<p>Exp1: Expected value from <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0...
Abstract Background Phenome-wide association studies (PheWAS) are a high-throughput approach to eval...
<p>Exp1: Expected value from <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0...
<p>Power was estimated at the nominal level of 5% based on 1,000 replicates. The value of <i>r</i><s...
<p>For each simulation setting where (or, equivalently, ), power was assessed by tracking the perce...
<p>Exp1: Expected value from <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0...
<p>For each effect size (1,2,3,4,5 or 10% of the total variance) 100 simulations were carried out. T...
<p>For each effect size (1,2,3,4,5 or 10% of the total variance) 100 simulations were carried out. T...
<p>For each effect size (1,2,3,4,5 or 10% of the total variance) 100 simulations were carried out. T...
<p>Results were based on 200 replicates. In each replicate, 500 cases and 500 controls were used to ...
<p>The figure shows the empirical power given the significance level of 0.05. Top row: 50 variants i...
The power of a statistical test is the probability that it will yield a statistically significant re...
<p>Power of detection for the different 2-locus models. Power was estimated as the proportion of ite...
<p>These values were averaged over ten simulations each. Note that these values differ slightly from...
The empirical power for scenarios (i)—(v) under nominal significance level 0.05 based on 10,000 repl...