Aflatoxin B₁ exposure down-regulates β-catenin expression in hepatoma carcinoma cell.

<p>(A) The protein levels of β-catenin in HeLa, AGS, Chang liver, Bel-7404 and HepG2 cell lines. (B) Relative cell viability of cells treated with AFB₁. (C) β-catenin protein levels are decrease in Chang liver and HepG2 cells treated with AFB₁ at their IC₅₀ value. (D) Relative levels of β-catenin protein in cells treated with AFB₁. The β-catenin protein levels were normalized with GADPH in (C). Data is presented as mean ± SD. *P < 0.05, **P < 0.01, ***P <0.001.