<p>WT, TLR2<sup>-/-</sup>, TLR9<sup>-/-</sup>, and TLR2/9<sup>-/-</sup> mice were exposed to SR 3 times / week for 3 weeks and analyzed 3 days after the last exposure. Representative H&E stained lung sections from unexposed WT mice (A), WT mice (B), TLR2<sup>-/-</sup> mice (C), TLR9<sup>-/-</sup> mice (D) and TLR2/9<sup>-/-</sup> mice (E) exposed to SR (Original magnification x4).</p
<p>WT mice (A,D,G,J), TNF<sup>−/−</sup> mice (B, E, H) and Tm-TNF mice (C,F,I,K) were infected by ae...
<p>VC (A, B) and GO 162 μg/mouse (C, D, E, F). (A and B) No pathological changes. (C) Patchy appeara...
<p>BALs from WT and TLR9<sup>-/-</sup> mice (n = 5 for each group) were collected 3 and 24 hours pos...
<p>WT, TLR2<sup>-/-</sup>, TLR9<sup>-/-</sup>, and TLR2/9<sup>-/-</sup> mice were exposed to SR and ...
<p>WT, TLR2<sup>-/-</sup>, TLR9<sup>-/-</sup>, and TLR2/9<sup>-/-</sup> mice were exposed to SR 3 ti...
<p>WT, TLR2<sup>-/-</sup>, TLR9<sup>-/-</sup> and TLR2/9<sup>-/-</sup> mice were exposed to SR 3 tim...
<p>WT, TLR2<sup>-/-</sup>, TLR9<sup>-/-</sup>, and TLR2/9<sup>-/-</sup> mice were exposed to SR 3 ti...
<p>Formalin-fixed, paraffin-embedded lung tissue was obtained at 7 weeks post-Mtb infection. Serial ...
<p>Bacterial burden in the lungs following aerosol infection with Mtb at doses of 100 CFU (A), 150 C...
<p>VC (A-C), GO 18 μg/mouse (D-F) or rGO 162 μg/mouse (G-I). (A-C) No pathological changes. (D-F) GO...
Type of granuloma development in Mtb-HT and Mtb-LT infected mice between 12–16 weeks following infec...
<p>Lungs and spleens were harvested from WT and TLR2KO mice, and single cell suspensions were prepar...
<p>Wild-type (WT) and Mincle<sup>−/−</sup> mice were injected intravenously with an oil-in-water emu...
<p>Histopathological analyses of lung sections were conducted at 14, 26 and 181 days post infection ...
<p>Lung tissue was harvested 3 hrs after CLP. Lysates were precipitated with anti-SRA and immunoblot...
<p>WT mice (A,D,G,J), TNF<sup>−/−</sup> mice (B, E, H) and Tm-TNF mice (C,F,I,K) were infected by ae...
<p>VC (A, B) and GO 162 μg/mouse (C, D, E, F). (A and B) No pathological changes. (C) Patchy appeara...
<p>BALs from WT and TLR9<sup>-/-</sup> mice (n = 5 for each group) were collected 3 and 24 hours pos...
<p>WT, TLR2<sup>-/-</sup>, TLR9<sup>-/-</sup>, and TLR2/9<sup>-/-</sup> mice were exposed to SR and ...
<p>WT, TLR2<sup>-/-</sup>, TLR9<sup>-/-</sup>, and TLR2/9<sup>-/-</sup> mice were exposed to SR 3 ti...
<p>WT, TLR2<sup>-/-</sup>, TLR9<sup>-/-</sup> and TLR2/9<sup>-/-</sup> mice were exposed to SR 3 tim...
<p>WT, TLR2<sup>-/-</sup>, TLR9<sup>-/-</sup>, and TLR2/9<sup>-/-</sup> mice were exposed to SR 3 ti...
<p>Formalin-fixed, paraffin-embedded lung tissue was obtained at 7 weeks post-Mtb infection. Serial ...
<p>Bacterial burden in the lungs following aerosol infection with Mtb at doses of 100 CFU (A), 150 C...
<p>VC (A-C), GO 18 μg/mouse (D-F) or rGO 162 μg/mouse (G-I). (A-C) No pathological changes. (D-F) GO...
Type of granuloma development in Mtb-HT and Mtb-LT infected mice between 12–16 weeks following infec...
<p>Lungs and spleens were harvested from WT and TLR2KO mice, and single cell suspensions were prepar...
<p>Wild-type (WT) and Mincle<sup>−/−</sup> mice were injected intravenously with an oil-in-water emu...
<p>Histopathological analyses of lung sections were conducted at 14, 26 and 181 days post infection ...
<p>Lung tissue was harvested 3 hrs after CLP. Lysates were precipitated with anti-SRA and immunoblot...
<p>WT mice (A,D,G,J), TNF<sup>−/−</sup> mice (B, E, H) and Tm-TNF mice (C,F,I,K) were infected by ae...
<p>VC (A, B) and GO 162 μg/mouse (C, D, E, F). (A and B) No pathological changes. (C) Patchy appeara...
<p>BALs from WT and TLR9<sup>-/-</sup> mice (n = 5 for each group) were collected 3 and 24 hours pos...