Effect of c-Myc Knockdown in Endothelial Cell Proliferation and Morphogenesis.

<p><b>A.</b> Time-course analysis of DNA synthesis in control and knockdown cells from 2–16 hours (n = 3–7). <b>B.</b> Representative images of stimulated control and knockdown cells collected 5 hours after incubation in Matrigel. <b>C.</b> Quantitative analysis of tube formation (n = 3–6). <b>D.</b> Quantification of control and knockdown cell adhesion to extracellular-matrix proteins (n = 5). *p<0.05, **p<0.005. NS, control; KD, knockdown; Col, collagen; FN, fibronectin; LN, laminin; TN, tenascin; VN, vitronectin. Magnification = 10X.