Ca²⁺ transients were larger and faster in field-stimulated myocytes from OVX mice compared to controls.

<p><b>A</b>. Ca²⁺ transients (top) and contractions (bottom) recorded in myocytes from sham and OVX mice (2 Hz). <b>B</b>. Peak contraction, normalized to resting cell length, was similar in sham and OVX myocytes. <b>C</b>,<b>D</b>. Mean time-to-peak and time-to-50% relaxation of contraction were reduced by OVX. <b>E</b>. Diastolic Ca²⁺ levels were similar in the two groups. <b>F</b>. Peak Ca²⁺ transients were larger in OVX cells than sham controls. <b>G</b>,<b>H</b>. Mean rate-of-rise and average rate of decay of the Ca²⁺ transient were both increased by OVX (n=25 sham and 26 OVX myocytes; *p<0.05; t-test).