γH2AX is persistent in <i>Meiob</i>^−/− spermatocytes.

<p>(<b>A</b>) <i>Meiob</i>^+/+ and <i>Meiob</i>^−/− spermatocyte chromosome spreads at various meiosis prophase I stages, stained for γH2AX, a marker of DNA DSBs, and SYCP3. (<b>B</b>) Histological sections of <i>Meiob</i>^+/+ and ^−/− adult testis stained for γH2AX. Scale bar, 40 µm. (<b>C</b>) γH2AX and SYCP1 are detected in <i>Meiob</i>^+/+ and <i>Meiob</i>^−/− spermatocyte chromosome spreads at pachytene and pachytene-like stages, respectively.