CXCR3 and its ligands are upregulated following <i>T. gondii</i> infection.

<p>(A) CXCR3, CXCL9, and CXCL10 gene expression was assessed by semi-quantitative real time PCR in mesenteric lymph nodes (MLN) and small intestinal tissue from WT mice during oral <i>T. gondii</i> infection. The results are expressed as fold change relative to tissues from noninfected animals (n = 4 mice per time point). (B) CXCR3 protein expression was quantified using flow cytometry by measuring GFP levels before (noninfected, NI) and 11 days after oral infection (INF) of CIBER mice. GFP levels were assessed among CD4⁺ and CD8⁺ T-cell subsets from MLN, spleen (SPL), and small intestinal lamina propria. NI, noninfected; INF, infected.