NK and NK T Cell Numbers in T. gondii-Infected CCR5<sup>−/−</sup> and CCR5<sup>+/+</sup> Mice in the C57BL/6 and C57BL/6x129 Backgrounds
- Imtiaz A Khan (17501)
- Seddon Y Thomas (17502)
- Magali M Moretto (17503)
- Frederick S Lee (17504)
- Sabina A Islam (17505)
- Crescent Combe (17506)
- Joseph D Schwartzman (17507)
- Andrew D Luster (17508)
Publication date
February 2013
DOIAbstract
<p>CCR5<sup>+/+</sup> and CCR5<sup>−/−</sup> mice in C57BL/6 and C57BL/6 × 129 backgrounds (three mice per group) were infected with 15 T. gondii cysts. At day 7 PI, lymphocytes from spleen (A and E), liver (B and F), blood (C and G), and mesenteric lymph nodes (D) were isolated and phenotyped for CD3<sup>+</sup> and NK1.1<sup>+</sup> by FACS analysis. NK1.1<sup>+</sup>CD3<sup>−</sup> and NK1.1<sup>+</sup>CD3<sup>+</sup> cell numbers are graphed. The experiment was performed twice with similar results.</p
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