<p>(A) The time period on the rotarod. (B) Total number of hind limb steps. Data are expressed as means ± SEM (n = 12). Statistical analyses were performed using one-way ANOVA. *<i>P</i> < 0.05, **<i>P</i> < 0.01 compared with the model (MPTP) group; ##<i>P</i> < 0.01 compared with the control group.</p
<p><b>A)</b> Following MPTP intoxication, animals displayed significantly reduced locomotor activity...
<p>Mice received a single injection (<i>i.p.</i>) of MPTP at 40 mg/kg or saline. AK7 30 mg/kg was in...
Parkinson's disease (PD) is a heterogeneous multi-systemic disorder unique to humans characterized b...
<p>Data are expressed as means ± SEM (n = 6). Statistical analyses were performed using one-way ANOV...
<p>Mice were analysed for motor deficit associated to PD with the catalepsy test. We observed that M...
<p>Body weights of mice during MPTP injection (5 consecutive days: A). *, compared to CON (rAAV-GFP+...
<p>(<b>A</b>) PM<sub>10</sub> Reduces MPTP-induced dopaminergic toxicity. MPTM-lesioned mice were tr...
<p>Motor function after MPTP was also assessed using a rotarod apparatus. At 8 days after the MPTP i...
<p>The mice were tested for Rotarod performance that measures the riding time (seconds) or endurance...
<p>Percentage of time spent on the accelerating rotarod (a) was measured over three separate trials ...
<p>Animal experiments were performed as described in <a href="http://www.plosone.org/article/info:do...
<p>A) Six to eight week old male C57BL/6 mice received 10 injections of MPTP (s.c.; 25 mg/kg body we...
Three common dosing regimens of the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced mode...
Parkinson's disease (PD) is an age-associated neurodegenerative disorder hallmarked by a loss of mes...
<p>The immunohistochemistry analysis revealed that the number of BrdU-positive cells decreased signi...
<p><b>A)</b> Following MPTP intoxication, animals displayed significantly reduced locomotor activity...
<p>Mice received a single injection (<i>i.p.</i>) of MPTP at 40 mg/kg or saline. AK7 30 mg/kg was in...
Parkinson's disease (PD) is a heterogeneous multi-systemic disorder unique to humans characterized b...
<p>Data are expressed as means ± SEM (n = 6). Statistical analyses were performed using one-way ANOV...
<p>Mice were analysed for motor deficit associated to PD with the catalepsy test. We observed that M...
<p>Body weights of mice during MPTP injection (5 consecutive days: A). *, compared to CON (rAAV-GFP+...
<p>(<b>A</b>) PM<sub>10</sub> Reduces MPTP-induced dopaminergic toxicity. MPTM-lesioned mice were tr...
<p>Motor function after MPTP was also assessed using a rotarod apparatus. At 8 days after the MPTP i...
<p>The mice were tested for Rotarod performance that measures the riding time (seconds) or endurance...
<p>Percentage of time spent on the accelerating rotarod (a) was measured over three separate trials ...
<p>Animal experiments were performed as described in <a href="http://www.plosone.org/article/info:do...
<p>A) Six to eight week old male C57BL/6 mice received 10 injections of MPTP (s.c.; 25 mg/kg body we...
Three common dosing regimens of the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced mode...
Parkinson's disease (PD) is an age-associated neurodegenerative disorder hallmarked by a loss of mes...
<p>The immunohistochemistry analysis revealed that the number of BrdU-positive cells decreased signi...
<p><b>A)</b> Following MPTP intoxication, animals displayed significantly reduced locomotor activity...
<p>Mice received a single injection (<i>i.p.</i>) of MPTP at 40 mg/kg or saline. AK7 30 mg/kg was in...
Parkinson's disease (PD) is a heterogeneous multi-systemic disorder unique to humans characterized b...