Spontaneous mutagenesis in strains deficient in histone H3 K56 deacetylation.

<p>With the exception of the first four strains, the strains are E134 (wild type) and its mutant derivatives. Fluctuation analyses and calculations of both mutation rates and 95% confidence intervals were performed as described in <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1003899#s4" target="_blank">Materials and Methods</a>. 95% confidence intervals are in parentheses. BY4742 strain lacks the <i>his7-2</i> reporter. The difference between two mutation rates marked with</p>a, b, or c<p> ^a, ^b, or ^c is not statistically significant (^ap = 0.17, ^bp = 0.06, and ^cp = 0.10).