Heatmaps for individual genes in primary (A) and secondary (B) metabolism (left panels) and clusters of genes around eight centers (right panels).

<p>Few primary metabolic genes are affected by <i>kmt6</i> mutation compared to the majority of secondary metabolic genes that have increased expression in <i>kmt6</i>. Values for the log₂ of the ratio of RPKMs for <i>kmt6</i>/WT or high/low nitrogen conditions for each strain are color-coded and the scale shown on the right. For example, in the left image of (A) red represents log₂ (<i>kmt6</i>/WT) of 10, which means the <i>kmt6</i> RPKM is 1024-fold higher than the WT RPKM. Primary metabolic genes in clusters 2 and 5, upregulated in <i>kmt6</i>, and cluster 7, downregulated in high nitrogen, are listed in <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1003916#pgen.1003916.s007" target="_blank">Table S2</a> with their putative functions. Secondary metabolic genes in clusters 1, 4, and 7, upregulated in <i>kmt6</i>, and cluster 8, downregulated in high nitrogen, are listed in <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1003916#pgen.1003916.s007" target="_blank">Table S2</a> with their putative functions.