Molecular Dynamics simulations (MDS).

<p>A. Plot of root mean square deviation (RMSD) of model 1L P_core Cα atoms versus simulation time, with respect to the starting structure coordinates. B, C, D and E. RMSD of model 2L, 1, 2 and 5L P_core Cα atoms using model 1L P_core as reference structure. F. Time- and residue-averaged root mean square fluctuations (RMSF) of all simulated models (1L to 5L and 1 to 5). The displayed curves represent average RMSF values over the four chains of a tetramer and two independent simulations.