HIV-specific CD8 T cell responses.

<p>Overview of longitudinal changes in magnitude of HIV-specific CD8 T cell responses towards overlapping screening peptides spanning Gag (white bars), Pol (black bars) and Nef (grey bars) in 7 early infected individuals (A), 4 chronically infected controllers (B) and 8 chronically infected progressors (C) as measured by Elispot assay. Exact peptide denomination follows in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0080045#pone-0080045-g002" target="_blank">Figure 2</a>. Only responses are depicted where sequencing of autologous virus was done subsequentially. X-axis: first and second time point of each individual. Y-axis: magnitude of CD8 T cell responses expressed in spot forming cells per million PBMC.