Predicted <i>miR135a</i> targets in the Wnt signaling pathway.

<p>A large number of genes involved in canonical Wnt signaling (including ligands, receptors and downstream transcriptional regulators) are bioinformatically predicted targets of <i>miR135a</i> by TargetScan and miRanda. A handful of genes (<i>Drapc1, Ctnnb1, Cav1, Cul3, Cxxc4, Dact1, Frat2, Lmna, Macf1, Pas5a, Porcn, Ppp2ca, Sost, Sostdc1, Wif1 and Wls</i>) were not found to be targets by these algorithms. This result suggests that <i>miR135a2</i> likely acts through multiple levels of the Wnt cascade to modulate Wnt signaling.