Large vesicular structures accumulate in <i>nrc^a14</i> photoreceptor inner segments.

<p>TEM images of cone photoreceptors in WT (A, B) and <i>nrc^a14</i> (C–E) 5 dpf retinas. Large vesicular structures were visible in approximately 80% of <i>nrc^a14</i> cone photoreceptor ISs. Some vesicular structures contained electron dense material (arrow heads, E). Boxes in A and C show areas enlarged in B and D respectively. Box in D shows area enlarged in E. OS = outer segment, N = nuclei. Scale bar = 2 µm in A–D, 1 µm in E.