Ultrastructural alterations in rods following acute light exposure in T4R RHO canine retinas.

<p>Transmission electron micrographs of photoreceptors from T4R RHO mutant and WT canine retinas at 15 min, 1 hour, and 6 hours after light exposure (LE) to a 1 min duration of white light (corneal irradiance: 1mW/cm²). Black arrowheads point to vesiculo-tubular structures located in the rod outer segments (ROS) and rod inner segments (RIS) of light exposed mutant retinas. Note that the CIS and COS remain normal even though there is extensive rod degeneration. CIS; cone inner segment; m: mitochondria.