Cardiac phospho-AMPK levels are decreased in hypertensive, diabetic mice.

<p>Western blot analysis of LV pAMPK levels in non-diabetic (Cn) and diabetic (DM) mice treated with vehicle or AngII (Ang) for 4 weeks. In the top panel, the quantification of LV pAMPK levels from 4–6 animals per group is shown. Data are analyzed by one-way ANOVA with Bonferroni post-hoc testing and expressed as mean±SEM. In the bottom panel, representative examples of pAMPK and GAPDH signals are shown for 2 animals per group. * refers to effect of AngII in non-diabetic and diabetic mice (* P<0.05, ** P<0.01, *** P<0.001) and # refers to effect of diabetes in vehicle-treated and AngII-treated mice (# P<0.05, ## P<0.01, ### P<0.001).