Effect of hypertension on cardiac AGE metabolism in non-diabetic and diabetic mice.

<p>Cardiac levels of GLO-1 protein (A), GLO-1 activity (B), CML (C), CEL (D), and MG-H1 (E) in non-diabetic (Cn) and diabetic (DM) mice treated with vehicle or AngII (Ang) for 4 weeks (age 18 weeks). Data are analyzed by one-way ANOVA with Bonferroni post-hoc testing and expressed as mean±SEM (n = 4–6 per group) * refers to effect of AngII in non-diabetic and diabetic mice (* P<0.05, ** P<0.01, *** P<0.001) and ^# refers to effect of diabetes in vehicle-treated and AngII-treated mice (# P<0.05, ## P<0.01, ### P<0.001).