Brain regions exhibiting significant group effect and their mean ReHo scores.

<p><b>Panel A</b> presents brain regions exhibiting significant group effect (two sample t-tests, thresholded at <i>p</i><0.05, AlphaSim corrected). Statistical maps (lateral, medial and anterior views) were projected onto the PALS (population-average, landmark, and surface-based) atlas using CARET software <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0085181#pone.0085181-VanEssen1" target="_blank">[72]</a>. The magnitude and direction of the t scores are represented by either warm (happy > unhappy) or cool (unhappy > happy) coloring. R.H. represents right hemisphere and L.H. represents left hemisphere. <b>Panel B</b> presents the mean ReHo scores for the Happy (red bars) and Unhappy (blue bars) group within the regions showing significant group effect. Error bars correspond to the standard error of mean. *: <i>p</i><0.05, **: <i>p</i><0.01, and ***: <i>p</i><0.001. Abbreviations: MPFC_B = bilateral medial prefrontal cortex; VLPFC_R = right ventrolateral prefrontal cortex; RSP_L = left retrosplenial cortex; STG_R = right superior temporal gyrus; PHG_R = right Parahippocampa Gyrus; HP_L = left hippocampus; SFG_R = right superior frontal gyrus; DLPFC_L = left dorsolateral prefrontal cortex; MCG_R = right middle cingulate gyrus; PT_R = right Putamen; TH_L = left Thalamus.