The quantitative comparison of GP4Rate and Rate4Site in the 2D toy protein simulations.

<p>(A) the ROC curves of GP4Rate and Rate4Site in the first configuration; (B) the ROC curves of GP4Rate and Rate4Site in the second configuration; (C) the losses of GP4Rate and Rate4Site in the first configuration; (D) the losses of GP4Rate and Rate4Site in the second configuration. In the ROC curves, the solid lines correspond to the performance of GP4Rate while the dotted lines correspond to the performance of Rate4Site. In the plots of losses, each point corresponds to a simulated alignment. The losses of the two methods are calculated by <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1003429#pcbi.1003429.e004" target="_blank">Equation 1</a>.