<p>Note: Numbers in the table represent number of animals per group for males and females. The first number indicates the number of pups assessed for developmental milestones, and the number in brackets indicates the number of animals that underwent behavioral testing. There were 3 litters in each of the 4 prenatal groups (2VEH, 5VEH: 2 or 5 injections of phosphate buffered saline vehicle on G15–16 or G12–16, respectively; LPS: Lipopolysaccharide, 50 ug/kg on G15–16; PPA: Propionic acid, 500 mg/kg on G12–16). Postnatal treatment during the second week of rat pups’ life consisted of phosphate buffered saline vehicle (VEH) or propionic acid (PPA). A maximum of 5 males and 5 females (3 postnatal PPA, 2 postnatal VEH for each sex) per litter we...
<p>Prenatal buprenorphine (0, 0.3, and 1 mg/kg/day) exposure was started from gestation day 7 and la...
The table summarizes the total number of animals per litter and the percentages of normal and abnorm...
<p>Information of the study population with number of dogs in each treatment group (probiotic (La1) ...
<p>Number of animals used per treatment group in the efficacy and safety experiments.</p
<p>The adult group includes parous and nulliparous rats in equal numbers. Therefore the total number...
<p>The weight curve from age p2 up to p32 of neurofascin- and control antibody treated pups in compa...
<p>Body weight at birth (postnatal day 0, PND0) (A), at PND7 (B) and at PND21 (C) of male and female...
<p>Number of animals studied and number of litters sampled for each experiment.</p
<p>A: Prenatal treatment – Pregnant dams received propionic acid (PPA) or vehicle once a day from ge...
As a multidisciplinary field, laboratory animal science promotes or accelerates the emergence of inn...
<p>Dosage groups for reproduction/developmental toxicity study in Wistar rats.</p
Figure S1. Birth outcomes are shown for: (A) litter size, (B) resorption numbers, determined by coun...
<p>Number of dogs tested, seroprevalence and coverage of the dog culling intervention by round of de...
<p>Total number of rats used in toxicity studies at the Safety Assessment Research Unit (black line)...
<p>A–B Males. C–D Females. Rats were prenatally exposed to either lipopolysaccharide (LPS) on G15–16...
<p>Prenatal buprenorphine (0, 0.3, and 1 mg/kg/day) exposure was started from gestation day 7 and la...
The table summarizes the total number of animals per litter and the percentages of normal and abnorm...
<p>Information of the study population with number of dogs in each treatment group (probiotic (La1) ...
<p>Number of animals used per treatment group in the efficacy and safety experiments.</p
<p>The adult group includes parous and nulliparous rats in equal numbers. Therefore the total number...
<p>The weight curve from age p2 up to p32 of neurofascin- and control antibody treated pups in compa...
<p>Body weight at birth (postnatal day 0, PND0) (A), at PND7 (B) and at PND21 (C) of male and female...
<p>Number of animals studied and number of litters sampled for each experiment.</p
<p>A: Prenatal treatment – Pregnant dams received propionic acid (PPA) or vehicle once a day from ge...
As a multidisciplinary field, laboratory animal science promotes or accelerates the emergence of inn...
<p>Dosage groups for reproduction/developmental toxicity study in Wistar rats.</p
Figure S1. Birth outcomes are shown for: (A) litter size, (B) resorption numbers, determined by coun...
<p>Number of dogs tested, seroprevalence and coverage of the dog culling intervention by round of de...
<p>Total number of rats used in toxicity studies at the Safety Assessment Research Unit (black line)...
<p>A–B Males. C–D Females. Rats were prenatally exposed to either lipopolysaccharide (LPS) on G15–16...
<p>Prenatal buprenorphine (0, 0.3, and 1 mg/kg/day) exposure was started from gestation day 7 and la...
The table summarizes the total number of animals per litter and the percentages of normal and abnorm...
<p>Information of the study population with number of dogs in each treatment group (probiotic (La1) ...