Effect of ACE inhibitors on blood ACE activity.

<p>Serum samples (1/5 dilution in PBS) from pool of 10 healthy volunteers (control) and from patient # 27 (arrowed in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0088001#pone-0088001-g001" target="_blank">Fig. 1 C</a>) were incubated with different concentration of ACE inhibitors: short –enalaprilat (<b>A</b>) and long –teprotide (<b>B</b>). Residual ACE activity was determined with two ACE substrates (and ZPHL/HHL ratio) as in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0088001#pone-0088001-g002" target="_blank">Fig. 2</a>. Data presented are mean ± SD of 2–3 independent experiments in duplicates). * p<0.05 vs. control serum.