Effect of <i>FoxC2</i> variant c.-512C>T (rs34221221) on luciferase expression in EA.hy926 cells.

<p>Cell lines were transiently transfected with the FoxC2 promoter reporter plasmid containing CC genotype or TT genotype. The renilla luciferase plasmid was co-transfected with reporter constructs to normalize the luciferase activity. Transfection with mutant construct (pGL4-TT) demonstrated a slight increase in luciferase activity (*p = 0.051) compared to wild pGL4-CC construct. Data shown are the mean ± SD of technical triplicates of two biological experiments.