<p>Superposition of three pharmacophore models Hypo A, Hypo B, and Hypo C, denoted in red, blue, and green, respectively.</p
<p>Color coding of pharmacophoric features: green, hydrophobic site; magenta, acceptor site; cyan, d...
<p>The model was generated from the 3D structure of PPT and its activities against CYP3A4. PPT fitte...
<p>Hypothesis features are color-coded as follows: hydrophobic aromatic, light blue; hydrogen bond d...
<p>Pharmacophore models (A) Hypo A, (B) Hypo B, and (C) Hypo C fitted to <b>22</b> and (D) overlay o...
<p>(A) Chemical features present in Hypo 1. (B) 3D spatial relationship and geometric parameters of ...
<p>Pharmacophore models (A) Hypo A, (B) Hypo B and (C) Hypo C fitted to <b>13</b>. The chemical feat...
<p>HBA, HBD, and HYP features are displayed in green, magenta, and cyan, respectively.</p
<p>Pharmacophore features are color-coded: cyan, hydrophobic (HY); orange, ring aromatic (RA); green...
<p>Generated pharmacophore models (A) Hypo A, (B) Hypo B and (C) Hypo C, in which hydrophobic, hydro...
<p>Generated pharmacophore models (A) Hypo A, (B) Hypo B, and (C) Hypo C, consisting of hydrogen-bon...
<p>(A) Hit1 (B) Hit2 (C) Hit3 (D) Hit4. HBA, HBD, and HYP features are displayed in green, magenta, ...
<p>The development of an optimal combination of pharmacophore models. Transparent boxes show the log...
<p>The light and dark green represent active and inactive features, respectively. The models mapped ...
<p>Pharmacophore features are defined as orange, green and purple colored represented by F1-aromatic...
<p>(A) Top scoring HypoGen pharmacophore Hypo1. (B) Hypo1 is aligned to the most active compound in ...
<p>Color coding of pharmacophoric features: green, hydrophobic site; magenta, acceptor site; cyan, d...
<p>The model was generated from the 3D structure of PPT and its activities against CYP3A4. PPT fitte...
<p>Hypothesis features are color-coded as follows: hydrophobic aromatic, light blue; hydrogen bond d...
<p>Pharmacophore models (A) Hypo A, (B) Hypo B, and (C) Hypo C fitted to <b>22</b> and (D) overlay o...
<p>(A) Chemical features present in Hypo 1. (B) 3D spatial relationship and geometric parameters of ...
<p>Pharmacophore models (A) Hypo A, (B) Hypo B and (C) Hypo C fitted to <b>13</b>. The chemical feat...
<p>HBA, HBD, and HYP features are displayed in green, magenta, and cyan, respectively.</p
<p>Pharmacophore features are color-coded: cyan, hydrophobic (HY); orange, ring aromatic (RA); green...
<p>Generated pharmacophore models (A) Hypo A, (B) Hypo B and (C) Hypo C, in which hydrophobic, hydro...
<p>Generated pharmacophore models (A) Hypo A, (B) Hypo B, and (C) Hypo C, consisting of hydrogen-bon...
<p>(A) Hit1 (B) Hit2 (C) Hit3 (D) Hit4. HBA, HBD, and HYP features are displayed in green, magenta, ...
<p>The development of an optimal combination of pharmacophore models. Transparent boxes show the log...
<p>The light and dark green represent active and inactive features, respectively. The models mapped ...
<p>Pharmacophore features are defined as orange, green and purple colored represented by F1-aromatic...
<p>(A) Top scoring HypoGen pharmacophore Hypo1. (B) Hypo1 is aligned to the most active compound in ...
<p>Color coding of pharmacophoric features: green, hydrophobic site; magenta, acceptor site; cyan, d...
<p>The model was generated from the 3D structure of PPT and its activities against CYP3A4. PPT fitte...
<p>Hypothesis features are color-coded as follows: hydrophobic aromatic, light blue; hydrogen bond d...
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