<p>A: Time course of changes in caspase 3/7 activity following carboplatin treatment. B: Western blot analysis of the levels of uncleaved PARP, cleaved PARP and cleaved (active) caspase 3 post 50 µM carboplatin treatment (0–96 h) in PC9 (i) and A549 cells (ii). C: Temporal changes in <sup>18</sup>F-ICMT-11 uptake in cells following carboplatin treatment. D: Correlation between caspase 3 activity and <sup>18</sup>F-ICMT-11 uptake in PC9 cells.</p
Cisplatin [ cis-PtCl2 NH3)2 ] is a widely utilized chemotherapeutic agent. Its proposed mechanism of...
<p>The RTCs were (A) transfected with PPARα overnight and (B) pretreated using various antagonists/i...
<p>* Apoptosis was measured through western blot for cleaved caspase 3 and cleaved PARP. (A&D) In ER...
<p>A: Chemical structure of <sup>18</sup>F-ICMT-11. B: Dose-dependent changes in caspase 3/7 activit...
<p>A: Carboplatin-induced growth inhibition in PC9 and A549 cells using a sulforhodamine B assay 72 ...
Tumour response to therapy is assessed primarily in the clinic by monitoring reductions in tumour si...
Tumour response to therapy is assessed primarily in the clinic by monitoring reductions in tumour si...
<p>(A) Box plots showing statistical distribution of the individual apoptosis rates, expressed as do...
<p>Caspase activity was assessed by fluorimetric or luminometric assays, as described in the Materia...
<p>Representative Western blot from pituitary primary cell extracts obtained as described in the Mat...
<p>(A) Time course (0–30 hours) fold increase in caspase 3/7, 8 and 9 activities of HT-29 cells post...
<p>A, HT-29 and T84 cells were treated for 24 h. Enzymatic activation of caspases 2, 3/7, 6, 8 and 9...
Investigating cell death signaling using cell culture is commonly performed to examine the effects o...
AbstractInvestigating cell death signaling using cell culture is commonly performed to examine the e...
<p>PBMCs from nine healthy volunteers were <i>ex vivo</i> treated (A) with cisplatin (0–300μg/ml) fo...
Cisplatin [ cis-PtCl2 NH3)2 ] is a widely utilized chemotherapeutic agent. Its proposed mechanism of...
<p>The RTCs were (A) transfected with PPARα overnight and (B) pretreated using various antagonists/i...
<p>* Apoptosis was measured through western blot for cleaved caspase 3 and cleaved PARP. (A&D) In ER...
<p>A: Chemical structure of <sup>18</sup>F-ICMT-11. B: Dose-dependent changes in caspase 3/7 activit...
<p>A: Carboplatin-induced growth inhibition in PC9 and A549 cells using a sulforhodamine B assay 72 ...
Tumour response to therapy is assessed primarily in the clinic by monitoring reductions in tumour si...
Tumour response to therapy is assessed primarily in the clinic by monitoring reductions in tumour si...
<p>(A) Box plots showing statistical distribution of the individual apoptosis rates, expressed as do...
<p>Caspase activity was assessed by fluorimetric or luminometric assays, as described in the Materia...
<p>Representative Western blot from pituitary primary cell extracts obtained as described in the Mat...
<p>(A) Time course (0–30 hours) fold increase in caspase 3/7, 8 and 9 activities of HT-29 cells post...
<p>A, HT-29 and T84 cells were treated for 24 h. Enzymatic activation of caspases 2, 3/7, 6, 8 and 9...
Investigating cell death signaling using cell culture is commonly performed to examine the effects o...
AbstractInvestigating cell death signaling using cell culture is commonly performed to examine the e...
<p>PBMCs from nine healthy volunteers were <i>ex vivo</i> treated (A) with cisplatin (0–300μg/ml) fo...
Cisplatin [ cis-PtCl2 NH3)2 ] is a widely utilized chemotherapeutic agent. Its proposed mechanism of...
<p>The RTCs were (A) transfected with PPARα overnight and (B) pretreated using various antagonists/i...
<p>* Apoptosis was measured through western blot for cleaved caspase 3 and cleaved PARP. (A&D) In ER...