Effect of FAK^I936/I998 expression on adhesion and migration.

<p>(A) For adhesion assay, cells were seeded in fibronectin-coated wells and allowed to adhere for 1 h before quantification. (P<0.0001, F = 28.96; 3 independent experiments done in sextuplicates). ***p<0.0001 versus FAK cells, ^†p<0.02 versus FAK^-/- cells. (B) For migration assays, confluent cell monolayers were wounded and cells were allowed to migrate for 8 h. Images were taken at t = 0 and t = 8 h, and the distance covered by migrated cells was evaluated. (P<0.0001, F = 21.57; 3 independent experiments done in triplicates). ***p<0.0001 versus FAK cells, *p<0.02 versus FAK cells, ^††p<0.005 versus FAK^-/- cells.