Role of apoptosis-associated genes in transduced DU145 cells.

<p>DU145 cells were transfected with TRAIL-R2,Gadd45a,TP53BP2 or HRK siRNA(20 nmol/L) or control siRNA (20 nmol/L) followed by transduction with Ad-G-AT2R-EGFP (100 ifu/cell) for 2 d. (<b>A</b>) siRNAs mediated-decrease of mRNA expression in transduced DU145 cells; (<b>B</b>) Green fluorescent cells exhibiting apoptotic morphology, which were counted from 10 fields per well.. Columns, mean of three experiments; bars, SE. *, P<0.05.