Effects of miR-34a on regulation of Ang II-induced myocardial hypertrophy.

<p>(<b>A</b>) qRT-PCR. The cardiomyocytes were treated with control lentivirus or Ang II plus control lentivirus or Ang II plus miR-34a mimics or Ang II plus miR-34a inhibitors and then subjected to qRT-PCR analysis of the hypertrophy-related genes ANP and β-MHC mRNA. *P<0.05 compared to NC; ^#P<0.05 compared to Ang II + NC. (<b>B</b>) Confocal microscopy. The cardiomyocyte morphology was measured by Confocal microscopy after staining with Alexa Fluor555 Phalloidin and DIPI. The graph summarizes the confocal microscopy data. *P<0.05 compared to NC; ^#P<0.05 compared to Ang II + NC.