A. Bodyweights in calorie restricted (CR), control, and diet-induced obesity (DIO) FVB mice.

<p>Bodyweight was measured weekly in all three dietary interventions. Each data point represents the mean of all the mice in that dietary group. B. Body fat in CR, control, and DIO dietary treatments. Dual-energy X-ray absorptiometer (DEXA) scans were conducted at the beginning of the study and after ten weeks of dietary treatment. Each bar represents the mean of ten mice per group. One-way analysis of variance (ANOVA) at the beginning of the study, p = 0.78. One-way ANOVA at ten weeks, p<0.001. <i>a</i>, <i>b</i>, and <i>c</i> represent dietary treatments that are significantly different from one another (p<0.05) as determined by Bonferroni test.