Effect of pEGFP-C2-HDAC2 plasmid on PTEN in HepG2 cells.

<p>HepG2 cells were treated with pEGFP-C2, pEGFP-C2-HDAC2 plasmid, pEGFP-C2-HDAC2 plasmid and melittin, pEGFP-C2-HDAC2 plasmid and TSA for 24 h. The PTEN mRNA expression was analyzed by real-time PCR (a). The PTEN protein expression was analyzed by Western blot (b). Relative PTEN mRNA and protein levels are presented as mean ± standard of the mean (S.E.) of optical densities from three separated experiments. **P<0.01 vs control and vector. ^#P<0.05 vs pEGFP-C2-HDAC2 plasmid group.