Expression of light and heavy myosin chains in chronic anthracycline cardiotoxicity and post-treatment follow up.

<p>Gene expression of cardiac myosin light chain isoform 1 (<b>A</b>, <b>D</b>) and isoform 2 (<b>B</b>, <b>E</b>) in the left and right ventricular myocardium, respectively. Western blot analysis of myosin light chain isoform 2 in the left (<b>C</b>) and right (<b>F</b>) ventricular myocardium. Gene expression of myosin heavy chain isoform α (<b>G</b>, <b>J</b>) and isoform β (<b>H</b>, <b>K</b>) in the left and right ventricular myocardium, respectively. Quantification of myosin heavy chains in the left (<b>I</b>) and right (<b>L</b>) ventricular myocardium. SYPRO Ruby stained 2.8% polyacrylamide gel strengthen with 0.75% agarose. Statistical significances (One Way ANOVA/One Way ANOVA on Ranks according to data character, <i>P</i><0.05) within each study period (*) or between the treatment and post-treatment period (#). C - control group, DAU - daunorubicin group.