Add to ORKGUsing quantitative RT-PCR in RNA from right ventricular (RV) endomyocardial biopsies from intact nonfailing hearts, and subjects with moderate RV failure from primary pul-monary hypertension (PPH) or idiopathic dilated cardiomy-opathy (IDC), we measured expression of genes involved in regulation of contractility or hypertrophy. Gene expression was also assessed in LV (left ventricular) and RV free wall and RV endomyocardium of hearts from end-stage IDC sub-jects undergoing heart transplantation or from nonfailing donors. In intact failing hearts, downregulation of
<p>Gene expression of cardiac myosin light chain isoform 1 (<b>A</b>, <b>D</b>) and isoform 2 (<b>B<...
Despite similar clinical endpoints, heart failure resulting from dilated cardiomyopathy (DCM) or hyp...
The development of cardiac hypertrophy secondary to pressure overload is accompanied by isoformic ch...
AbstractIn the mammalian heart, the development of cardiac hypertrophy is a common feature that norm...
In the mammalian heart, the development of cardiac hypertrophy is a common feature that normally pre...
The physiology of myocardial contractility has been studied for over a century, but only recently ha...
The present study investigated whether functional, molecular, and biochemical alterations occurring ...
Hemodynamic overload produces in the cardiac myocyte a complex pattern of gene reprogramming, a 'mec...
The adult rodent heart adapts to increased work load by reexpression of its fetal genes, for example...
We have previously described a quantitative method for measuring mRNA abundance in endomyocardial bi...
The expression of genes changes during left ventricular hypertrophy. These changes are known as mech...
Hypertrophic cardiomyopathy (HCM) is the most common genetic cardiomyopathy. The molecular mechanism...
The expression of genes changes during left ventricular hypertrophy. These changes are known as mech...
AIM: The aim of the study was to compare the functional and structural properties of the motor prote...
Background—In patients with end-stage heart failure, characterized by an increased susceptibility to...
<p>Gene expression of cardiac myosin light chain isoform 1 (<b>A</b>, <b>D</b>) and isoform 2 (<b>B<...
Despite similar clinical endpoints, heart failure resulting from dilated cardiomyopathy (DCM) or hyp...
The development of cardiac hypertrophy secondary to pressure overload is accompanied by isoformic ch...
AbstractIn the mammalian heart, the development of cardiac hypertrophy is a common feature that norm...
In the mammalian heart, the development of cardiac hypertrophy is a common feature that normally pre...
The physiology of myocardial contractility has been studied for over a century, but only recently ha...
The present study investigated whether functional, molecular, and biochemical alterations occurring ...
Hemodynamic overload produces in the cardiac myocyte a complex pattern of gene reprogramming, a 'mec...
The adult rodent heart adapts to increased work load by reexpression of its fetal genes, for example...
We have previously described a quantitative method for measuring mRNA abundance in endomyocardial bi...
The expression of genes changes during left ventricular hypertrophy. These changes are known as mech...
Hypertrophic cardiomyopathy (HCM) is the most common genetic cardiomyopathy. The molecular mechanism...
The expression of genes changes during left ventricular hypertrophy. These changes are known as mech...
AIM: The aim of the study was to compare the functional and structural properties of the motor prote...
Background—In patients with end-stage heart failure, characterized by an increased susceptibility to...
<p>Gene expression of cardiac myosin light chain isoform 1 (<b>A</b>, <b>D</b>) and isoform 2 (<b>B<...
Despite similar clinical endpoints, heart failure resulting from dilated cardiomyopathy (DCM) or hyp...
The development of cardiac hypertrophy secondary to pressure overload is accompanied by isoformic ch...