<p>(a) <i>fliY</i> promoter activity dynamics in 15 different measured conditions (15 combinations of conditions A,B,C,D). (b) First two principal components dynamics of <i>fliY</i>, according to principal component analysis of <i>fliY</i> dynamics in all conditions and combinations. (c) Fraction of variance explained by the first two principal components for all 94 promoters in 15 environments. Red arrows: <i>fliY</i> and rrnB with 91% and 99% explained variance. (d) <i>rrnB</i> promoter activity dynamics in 15 different measured conditions (e) The first PC of <i>rrnB</i> according to principal component analysis of <i>rrnB</i> expression dynamics in all conditions and combinations. (f) Fraction of variance explained by only the first prin...
promoter region, where each sequence is associated with its phenotype, the induced transcriptional ...
In (A), independent regulation causes the reduction in variation to be restricted to context 1 (cont...
<p>(A) Schematic of a single target promoter sharing TFs with multiple competitor sites. (B) The var...
<div><p>Bacteria often face complex environments. We asked how gene expression in complex conditions...
<p>Six representative promoters are shown (each row belongs to one promoter. The Promoter name is in...
Accurate characterization of promoter activity is important when designing expression systems for sy...
Accurate characterization of promoter behavior is essential for the rational design of functional sy...
<p>(a) The Principal component analysis (PCA) energy ranking, in which the top five Principal compon...
<p>(a) <i>E. coli</i> reporter strains were grown in defined media conditions in 96-well plates and ...
<p>The promoter region -with the TSS highlighted- and the codifying region are pointed out. Most of ...
<p>Significant correlation among the four CpGs in <i>PLA2G7</i> gene promoter.</p
Recent experimental studies have reported that cell-to-cell variability in gene expression is a univ...
<p>a) Predicted relationship between mean and variance using original model with original parameter ...
AbstractGenes in eukaryotic cells are typically regulated by complex promoters containing multiple b...
AbstractTranscription is regulated through interplay among transcription factors, an RNA polymerase ...
promoter region, where each sequence is associated with its phenotype, the induced transcriptional ...
In (A), independent regulation causes the reduction in variation to be restricted to context 1 (cont...
<p>(A) Schematic of a single target promoter sharing TFs with multiple competitor sites. (B) The var...
<div><p>Bacteria often face complex environments. We asked how gene expression in complex conditions...
<p>Six representative promoters are shown (each row belongs to one promoter. The Promoter name is in...
Accurate characterization of promoter activity is important when designing expression systems for sy...
Accurate characterization of promoter behavior is essential for the rational design of functional sy...
<p>(a) The Principal component analysis (PCA) energy ranking, in which the top five Principal compon...
<p>(a) <i>E. coli</i> reporter strains were grown in defined media conditions in 96-well plates and ...
<p>The promoter region -with the TSS highlighted- and the codifying region are pointed out. Most of ...
<p>Significant correlation among the four CpGs in <i>PLA2G7</i> gene promoter.</p
Recent experimental studies have reported that cell-to-cell variability in gene expression is a univ...
<p>a) Predicted relationship between mean and variance using original model with original parameter ...
AbstractGenes in eukaryotic cells are typically regulated by complex promoters containing multiple b...
AbstractTranscription is regulated through interplay among transcription factors, an RNA polymerase ...
promoter region, where each sequence is associated with its phenotype, the induced transcriptional ...
In (A), independent regulation causes the reduction in variation to be restricted to context 1 (cont...
<p>(A) Schematic of a single target promoter sharing TFs with multiple competitor sites. (B) The var...